The Fluvian mansion stands in the heart of Rhodes' Medieval Town, a place rich in history that stretches far beyond the building itself. When the Dodecanese became part of Italy in 1912, many properties were officially recorded for the first time. Historical records show that a group of Ottoman-owned houses once stood on this site.

These houses were destroyed during World War II, when a German bomb, aimed at the nearby shelter, the well-known Promachona, struck the compound. The land was later purchased by our great-grandfather, Nikitas Papanikitas, a priest from Karpathos.

In the 1950s, Nikitas's sons, Nikos and Ioannis, used the space as the headquarters of their road construction company. In the 1960s, the property took on a more creative role, as Ioannis established a tile-making workshop. As life and business on Rhodes continued to grow, he eventually relocated his work to the town center, and the space was later rented to a woodworking workshop.

In 1984, Michael Papanikitas, a doctor, inherited the property and envisioned bringing family life back to it. Over the following years, he dedicated himself to building the villa, inspired by his love for the Old Town. The house was expanded with the addition of a second floor in 2010, and in 2019, Villa Fluvian welcomed its first guests, who traveled all the way from Sydney.